Structural basis for lipid transfer by the ATG2A-ATG9A complex
Yang Wang, Selma Dahmane, Rujuan Ti, Xinyi Mai, Lizhe Zhu, Lars-Anders Carlson, Goran Stjepanovic
Nat Struct Mol Biol, 2024 Aug 22. pubmed
In vitro reconstitution reveals membrane clustering and RNA recruitment by the enteroviral AAA+ ATPase 2C
Kasturika Shankar, Marie N Sorin, Himanshu Sharma, Oskar Skoglund, Selma Dahmane, Josy Ter Beek, Solomon Tesfalidet, Louise Nenzén, Lars-Anders Carlson
PLoS Pathogens. 2024 Aug 5;20(8):e1012388. pubmed
A chemical inhibitor of IST1-CHMP1B interaction impairs endosomal recycling and induces noncanonical LC3 lipidation
Anastasia Knyazeva, Shuang Li, Dale P Corkery, Kasturika Shankar, Laura K Herzog, Xuepei Zhang, Birendra Singh, Georg Niggemeyer, David Grill, Jonathan D Gilthorpe, Massimiliano Gaetani, Lars-Anders Carlson, Herbert Waldmann, Yao-Wen Wu
Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2317680121. pubmed
Ultrastructural insights into the microsporidian infection apparatus reveal the kinetics and morphological transitions of polar tube and cargo during host cell invasion
Himanshu Sharma, Nathan Jespersen, Kai Ehrenbolger, Lars-Anders Carlson, Jonas Barandun
PLoS Biology. 2024 Feb 29;22(2):e3002533. pubmed
The organization of double-stranded RNA in the chikungunya virus replication organelle
Timothée Laurent, Lars-Anders Carlson.
PLOS Neglected Tropical Diseases. 2023 Jul 5;17(7):e0011404. pubmed
Type I interferon shapes brain distribution and tropism of tick-borne flavivirus
Nunya Chotiwan, Ebba Rosendal, Stefanie MA Willekens, Erin Schexnaydre, Emma Nilsson, Richard Lindqvist, Max Hahn, Ionut Sebastian Mihai, Federico Morini, Jianguo Zhang, Gregory D Ebel, Lars-Anders Carlson, Johan Henriksson, Ulf Ahlgren, Daniel Marcellino, Anna K Överby
Nature Communications. 2023 Apr 10;14(1):2007. pubmed
A 3D view of how enteroviruses hijack autophagy
Selma Dahmane, Kasturika Shankar, Lars-Anders Carlson
Autophagy. 2022 Dec 5;1-3 pubmed
Architecture of the chikungunya virus replication organelle
Timothée Laurent, Pravin Kumar, Susanne Liese, Farnaz Zare, Mattias Jonasson, Andreas Carlson, Lars-Anders Carlson
eLife 2022 Oct 19;11:e83042 pubmed
Membrane-assisted assembly and selective secretory autophagy of enteroviruses
Selma Dahmane, Adeline Kerviel, Dustin R. Morado, Kasturika Shankar, Björn Ahlman, Michael Lazarou, Nihal Altan-Bonnet, Lars-Anders Carlson
Nature Communications. 2022 Oct 10. 13, 5986. pubmed
V. cholerae MakA is a cholesterol-binding pore-forming toxin that induces non-canonical autophagy
Xiaotong Jia, Anastasia Knyazeva, Yu Zhang, Sergio Castro-Gonzalez, Shuhei Nakamura, Lars-Anders Carlson, Tamotsu Yoshimori, Dale P Corkery, Yao-Wen Wu
J Cell Biol. 2022 Dec 5;221(12):e202206040 pubmed
The Tetraspanin CD81 Is a Host Factor for Chikungunya Virus Replication
Lisa Lasswitz, Francisco J Zapatero-Belinchón, Rebecca Moeller, Kirsten Hülskötter, Timothée Laurent, Lars-Anders Carlson, Christine Goffinet, Graham Simmons, Wolfgang Baumgärtner, Gisa Gerold
mBio. 2022 Jun 28;13(3):e0073122 pubmed
Clinically observed deletions in SARS-CoV-2 Nsp1 affect its stability and ability to inhibit translation
Pravin Kumar, Erin Schexnaydre, Karim Rafie, Tatsuaki Kurata, Ilya Terenin, Vasili Hauryliuk, Lars-Anders Carlson
FEBS Letters. 2022 Apr 17 pubmed
The structure of enteric human adenovirus 41—A leading cause of diarrhea in children
Karim Rafie, Annasara Lenman, Johannes Fuchs, Anandi Rajan, Niklas Arnberg, Lars-Anders Carlson
Science Advances. 2021 Jan 8;7(2) pubmed
Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD46
B David Persson, Lijo John, Karim Rafie, Michael Strebl, Lars Frängsmyr, Monika Z Ballmann, Katja Mindler, Menzo Havenga, Angelique Lemckert, Thilo Stehle, Lars-Anders Carlson, Niklas Arnberg
Proc Natl Acad Sci U S A. 2021 Jan 19;118(3) pubmed
A ribonucleotide reductase from Clostridium botulinum reveals distinct evolutionary pathways to regulation via the overall activity site
Markel Martínez-Carranza, Venkateswara Rao Jonna, Daniel Lundin, Margareta Sahlin, Lars-Anders Carlson, Newal Jemal, Martin Högbom, Britt-Marie Sjöberg, Pål Stenmark, Anders Hofer
J Biol. Chem. 2020 Nov 13;295(46):15576-15587 pubmed
ATP-dependent force generation and membrane scission by ESCRT-III and Vps4
Johannes Schöneberg, Mark Remec Pavlin, Shannon Yan, Maurizio Righini, Il-Hyung Lee, Lars-Anders Carlson, Amir Houshang Bahrami, Daniel H. Goldman, Xuefeng Ren, Gerhard Hummer, Carlos Bustamante, James H. Hurley
Science. 2018 Dec 21;362(6421):1423-1428. pubmed
Neutralizing Antibodies Inhibit Chikungunya Virus Budding at the Plasma Membrane
Jing Jin, Jesús G Galaz-Montoya, Michael B Sherman, Stella Y Sun, Cynthia S Goldsmith, Eileen T O’Toole, Larry Ackerman, Lars-Anders Carlson, Scott C Weaver, Wah Chiu, Graham Simmons
Cell Host Microbe. 2018 Aug 18. pii: S1931-3128(18)30388-3. pubmed
An attenuated replication-competent chikungunya virus with a fluorescently tagged envelope
Jing Jin, Michael B Sherman, Daniel Chafets, Nuntana Dinglasan, Kai Lu, Tzong-Hae Lee, Lars-Anders Carlson, Marcus O Muench, Graham Simmons
PLoS Negl Trop Dis. 2018 Jul 31;12(7):e0006693 pubmed
Reconstitution of selective HIV-1 RNA packaging in vitro by membrane-bound Gag assemblies
Lars-Anders Carlson*, Yun Bai, Sarah C Keane, Jennifer A Doudna, James H Hurley*
Elife. 2016 Jun 25;5 pubmed
*co-corresponding
Negative membrane curvature catalyzes nucleation of endosomal sorting complex required for transport (ESCRT)-III assembly
Il-Hyung Lee, Hiroyuki Kai, Lars-Anders Carlson, Jay T Groves, James H Hurley
Proc Natl Acad Sci U S A. 2015 Dec 29;112(52) pubmed
ESCRT filaments as spiral springs
Lars-Anders Carlson, Qing-Tao Shen, Mark Remec Pavlin, James H Hurley
Dev Cell. 2015 Nov 23;35(4) pubmed
Architecture and dynamics of the autophagic phosphatidylinositol 3-kinase complex
Sulochanadevi Baskaran*, Lars-Anders Carlson*, Goran Stjepanovic*, Lindsey N Young, Patricia Grob, Robin E Stanley, Eva Nogales, James H Hurley
Elife. 2014 Dec 9;3 pubmed
*equal contribution
The nucleocapsid domain of Gag is dispensable for actin incorporation into HIV-1 and for association of viral budding sites with cortical F-actin
Sarah Stauffer, Sheikh Abdul Rahman, Alex de Marco, Lars-Anders Carlson, Bärbel Glass, Heike Oberwinkler, Nikolas Herold, John AG Briggs, Barbara Müller, Kay Grünewald, Hans-Georg Kräusslich
J Virol. 2014 Jul;88(14) pubmed
In vitro reconstitution of the ordered assembly of the endosomal sorting complex required for transport at membrane-bound HIV-1 Gag clusters
Lars-Anders Carlson, James H Hurley
Proc Natl Acad Sci U S A. 2012 Oct 16;109(42) pubmed
Endosomal sorting complex required for transport (ESCRT) complexes induce phase-separated microdomains in supported lipid bilayers
Evzen Boura, Vassili Ivanov, Lars-Anders Carlson, Kiyoshi Mizuuchi, James H Hurley
J Biol Chem. 2012 Aug 10;287(33) pubmed
Membrane budding
James H Hurley, Evzen Boura, Lars-Anders Carlson, Bartosz Różycki
Cell. 2010 Dec 10;143(6) pubmed
Cryo electron tomography of native HIV-1 budding sites
Lars-Anders Carlson, Alex de Marco, Heike Oberwinkler, Anja Habermann, John AG Briggs, Hans-Georg Kräusslich, Kay Grünewald
PLoS Pathog. 2010 Nov 24;6(11) pubmed
The three-dimensional organization of polyribosomes in intact human cells
Florian Brandt*, Lars-Anders Carlson*, F Ulrich Hartl, Wolfgang Baumeister, Kay Grünewald
Mol Cell. 2010 Aug 27;39(4) pubmed
*equal contribution
Three-dimensional analysis of budding sites and released virus suggests a revised model for HIV-1 morphogenesis
Lars-Anders Carlson, John AG Briggs, Bärbel Glass, James D Riches, Martha N Simon, Marc C Johnson, Barbara Müller, Kay Grünewald, Hans-Georg Kräusslich
Cell Host Microbe. 2008 Dec 11;4(6) pubmed
Test of relativistic time dilation with fast optical atomic clocks at different velocities
Sascha Reinhardt, Guido Saathoff, Henrik Buhr, Lars-Anders Carlson, Andreas Wolf, Dirk Schwalm, Sergei Karpuk, Christian Novotny, Gerhard Huber, Marcus Zimmermann, Ronald Holzwarth, Thomas Udem, Theodor W Hänsch, Gerald Gwinner
Nature Physics. 2007 3 (12) Google Scholar
Test of time dilation by laser spectroscopy on fast ions
Guido Saathoff, Sascha Reinhardt, Henrik Buhr, Lars-Anders Carlson, Dirk Schwalm, Andreas Wolf, Sergei Karpuk, Chistian Novotny, Gerhard Huber, Gerald Gwinner
Canadian Journal of Physics. 2005 83 (4) Google Scholar
Assessment of production conditions for efficient use of Escherichia coli in high-yield heterologous recombinant selenoprotein synthesis
Olle Rengby, Linda Johansson, Lars-Anders Carlson, Elena Serini, Alexios Vlamis-Gardikas, Per Kårsnäs, Elias SJ Arnér
Appl Environ Microbiol. 2004 Sep;70(9) pubmed